The Role of Contact Dermatitis in Patients with Atopic Dermatitis

July–August, 2014 Volume 2, Issue 4, Pages 382–387

Marcella Aquino, MD

,

 Luz Fonacier, MD

Section of Allergy and Clinical Immunology, Department of Medicine, Winthrop University Hospital, Mineola, NY

Received: January 28, 2014; Received in revised form: May 6, 2014; Accepted: May 7, 2014;

DOI: http://dx.doi.org/10.1016/j.jaip.2014.05.004

Article Info

• Abstract
• Full Text
• References

Because both atopic dermatitis (AD) and contact dermatitis (CD) are characterized by a similar morphologic appearance and similar distribution of skin involvement, the diagnosis of CD in AD has been difficult.

Historically, it was thought that patients with AD were unable or less likely to develop CD due to various studies in which patients with AD stimulated with strong allergens failed to develop sensitization at rates similar to patients without AD. However, more recent evidence from the United States and Europe has shown that patients with AD have similar if not higher rates of positive patch test results to common contact allergens, including metals and fragrance, than those patients without AD. In this review, we highlight evidence for and against the role of contact allergy in patients with AD and seek to give clinically relevant management recommendations for the evaluation of CD in the patient with AD.

Key words:

Allergic contact dermatitis, Irritant contact dermatitis, Atopic dermatitis, Patch test